High-Throughput Screening of Natural Products for Cancer Therapy
نویسندگان
چکیده
منابع مشابه
High-throughput screening of natural products for cancer therapy.
Natural products have been the biggest single source of anticancer drugs and there are continued efforts to explore the chemical diversity provided by nature in order to find new lead compounds. Bioassay test methods have developed into high throughput screening assays using both cell-based and molecular approaches. The various ways to detect effects on cell viability and cell proliferation are...
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The menace of cervical cancer has reached an alarming rate. There are more than 450.000cases of cervical cancer yearly, with mortality rate of about 50%. This deadly cancer is causedby human papillomavirus (HPV), mainly subtypes 16 and 18. The pharmaceutical industryhas produced drug for combating the virus, known as SAHA (suberoylanilide hydroxamicacid). It inhibits class II HDAC Homo sapiens ...
متن کاملExposing the Molecular Screening Method of Indonesian Natural Products Derivate as Drug Candidates for Cervical Cancer
The menace of cervical cancer has reached an alarming rate. There are more than 450.000cases of cervical cancer yearly, with mortality rate of about 50%. This deadly cancer is causedby human papillomavirus (HPV), mainly subtypes 16 and 18. The pharmaceutical industryhas produced drug for combating the virus, known as SAHA (suberoylanilide hydroxamicacid). It inhibits class II HDAC Homo sapiens ...
متن کاملNatural Products for Cancer Therapy
2Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, UPM Serdang-43400, Malaysia 3Department of Medical Laboratory Sciences, College of Health Sciences, Komar University of Science and Technology, ChaqChaq-Qularasisy, Kurdistan Region, Northern Iraq *Corresponding author: Heshu Sulaiman Rahman, Department of Veterinary Clinical Scienc...
متن کاملMicrotubule-binding natural products for cancer therapy.
Natural products, especially microtubule-binding natural products, play important roles in the war against cancer. From the clinical use of vinblastine in 1961, paclitaxel in 1992, to ixabepilone in 2007, microtubule-binding natural products have continually contributed to the development of cancer therapy. The present review summarizes the development of representative microtubule-binding natu...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2010
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-0030-1250162